Basic Information
VIS ID
TVIS10019045
Fusion event
HBV-CERS6 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr2
Cytoband
q24.3
Reference genome
GRCh37.55
Start
169610239/168753729 (Hg38)
End
169610239/168753729 (Hg38)
Location type
Intron8
Target gene
CERS6
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-21-5p ; hsa-mir-6511b-3p ; hsa-mir-7159-3p ; hsa-mir-5088-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-4762-5p ; hsa-mir-425-5p ; hsa-mir-3591-3p ; hsa-mir-21-3p ; hsa-mir-551b-5p ; hsa-mir-548c-3p
Nearest miRNA
hsa-mir-128-1/Upstream/170711; hsa-mir-10b/Downstream/6413904;
Nearest TSS
ENST00000437798/Upstream/297480; ENST00000471833/Downstream/32810;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/296617, chr2-CpG: 22/Downstream/136480
Upstream sequence
acggtgaggggagggaaggtcagagagaccttgaggctttttcagttgtgtatgtcaaagcgccatgctttgggacttctgaccccaataCCTCTGGCTA
Downstream sequence
GTGAAGACTTAATCTTGTCAATATTTAAATAAAAACAGACCTTTATTTTAAAGTATTGTAACACTTCCAGTAGAATCTATACATGTTTAGAATTCCATGC
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate