VISDB Viral Integration Site DataBase

VIS ID

TVIS10019052

Fusion event

HBV-FBXL7 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr5

Cytoband

p15.1

Reference genome

Start

End

15616388/15616279 (Hg38)

Location type

Exon2

Target gene

miRNAs that regulate target gene

hsa-mir-3912-5p ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-5681b ; hsa-mir-31-3p ; hsa-mir-571 ; hsa-mir-219a-1-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-4461 ; hsa-mir-5579-5p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p

Nearest miRNA

hsa-mir-10397/Upstream/790059; hsa-mir-103a-1/Downstream/318903;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/115257, chr5-CpG: 34/Downstream/311700

Upstream sequence

CATCATCCATGTACCTAGAGTAAAGAAAGGAGTGTGGTCCATTCTTCCTCTCTTCCACTCTTCTGTCCCCTATTCACTAGGCAATGACCTCCCTTCCTGA

Downstream sequence

CAGGTGCCTCAATTATAAGGCAAATGTTGTTTTGTGAAAATGGAATAGGCTGAATTAAGGGAAGGCTTTACAATATCATATACCTTGTCTTTCCGTATAA

Target sequence

GGTAGGCAGCTGGTCTTCATTATCTCTCTTTCTTCTTCACAGGGCTGGCTATTTTTGGAACAGAAATAAAGTGTGGGAGTGTTAGTTCTATTCTCCTGAGTGGGAGCATATGAGATCTTAAAAATGAGGATGTTCAGGGTCTCCTAAGTTTTGTTGTTGTTGTTGTTGCGCTGCAGTTACAGTTCATGAAAATTGATTTGACGGGATT