Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019057
Fusion event
HBV-CDK14 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Host Sequence
Chromosome
chr7
Cytoband
q21.13
Reference genome
Start
End
90505499/90876184 (Hg38)
Location type
Intron5
Target gene
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-26b-5p ; hsa-mir-376c-3p ; hsa-mir-493-5p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-6785-5p ; hsa-mir-6883-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-4533 ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-6783-5p ; hsa-mir-4419a ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6873-5p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-4428
Nearest miRNA
hsa-mir-10525/Upstream/14960915; hsa-mir-10399/Downstream/1327831;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/279134, chr7-CpG: 255/Downstream/388094
Nearest cancer related gene
CDK14(OG, No orient, 0)
Upstream sequence
CGGCTGCCGCCCCAGCCCGCTTCCCCTCCTCACGTCCTTCCCTGCGCCTGGAGGTCTCCCCTGACCGTCCCGCAGCTGAAATCTTGGCCTCGCTGTCCGC
Downstream sequence
accctcaatgccagtatccgtctttcctgtgatgctatgagattcccaatgaaaaaacttccaaactcctgcctggctgccaatcttctggaaactgagt
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.