RELN _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019058
Fusion event
HBV-RELN integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr7
Cytoband
q22.1
Reference genome
GRCh37.55
Start
103468198/103827751 (Hg38)
End
103468198/103827751 (Hg38)
Location type
Intron61
Fragile sites / regions
FRA7F
Target gene
RELN
miRNAs that regulate target gene
hsa-mir-128-3p ; hsa-mir-138-5p ; hsa-mir-10a-5p
Nearest miRNA
hsa-mir-10525/Upstream/1356220; hsa-mir-10399/Downstream/10825594;
Nearest TSS
ENST00000635602/Upstream/197615; ENST00000401970/Downstream/161765;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/381358, chr7-CpG: 122/Downstream/161327
Upstream sequence
tgagccactgcacccCATGGACACTTCTCTTAAAACTAGATTAAATAGTGGCATCTTTGACTTGAATAAATGTCTGCAAGTAGTGGGTCTTTTGGGTTTT
Downstream sequence
GCACTGACATTGTCTCAAGTTGGGAGATGCCTGCTTAAAAACAGAAAACTAGACTGTCAGAAAAGAAAAAAAAGACGTGATTTAAAAGAAAGATGAAATT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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