GUCY1A2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019065
Fusion event
HBV-GUCY1A2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr11
Cytoband
q22.3
Reference genome
GRCh37.55
Start
106641804/106771078 (Hg38)
End
106642414/106771688 (Hg38)
Location type
Intron2
Target gene
GUCY1A2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-3619-3p ; hsa-mir-3917 ; hsa-mir-7705 ; hsa-mir-6512-5p ; hsa-mir-625-3p ; hsa-mir-145-3p ; hsa-mir-1288-5p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-330-3p
Nearest miRNA
hsa-mir-10392/Upstream/2921098; hsa-let-7a-2/Downstream/4576069;
Nearest TSS
ENST00000527297/Upstream/638962; ENST00000529675/Downstream/246463;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/692989, chr11-CpG: 137/Downstream/245909
Upstream sequence
AGATCTTAATAAATGTTGCAGCTTTGACATGGAAGCAATGCTGTAGCTGTCATAGGGCTTAACAACAAGGCGTGCTACTTCAAAACCTCCCAGCAGACCT
Downstream sequence
ctgtagtaagctgtgatggtgacactgcactccagcctggacaacagagcaagaccctgtgtcttgaggaaaaaaaacaagaaaaTCAGATTCTCCCTTG
Target sequence
AAAAGACATTTGGACATACTCAATATTCTTCAAAAGCCTTAAATCGTGAAAATGCTATTTGTCTTTCTCATATACCCTAGGTACATTCTCTAGTTAATCCTTGACCCAACTTCCCTTTCCCTATCAACAGTGTTTTTTAAAGAAAGAATAAGTCATAGGCAGTAATAAATATTTGGTTATTTTAATCAAAGTGTGGTTAAACTATTAGTGTAAGTTAGCCAGTCAGCACTAAAAACTATTCAAAATACCTTTGGG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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