VISDB Viral Integration Site DataBase

VIS ID

TVIS10019070

Fusion event

HBV-RBFOX2 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr22

Cytoband

q12.3

Reference genome

Start

End

36419380/36023332 (Hg38)

Location type

Intron13

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-320d ; hsa-mir-498 ; hsa-mir-9-5p ; hsa-mir-32-5p ; hsa-mir-30a-5p ; hsa-let-7b-5p ; hsa-mir-186-5p ; hsa-let-7a-5p ; hsa-mir-3923 ; hsa-mir-432-3p ; hsa-mir-432-5p ; hsa-mir-106a-3p ; hsa-mir-203b-3p ; hsa-mir-7154-5p ; hsa-mir-4755-3p ; hsa-mir-628-3p ; hsa-mir-8060 ; hsa-mir-4650-5p ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-6858-3p ; hsa-mir-25-3p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-921 ; hsa-mir-1294 ; hsa-mir-630 ; hsa-mir-202-3p ; hsa-mir-3163 ; hsa-mir-3174 ; hsa-mir-548l ; hsa-mir-3133 ; hsa-mir-548n ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-98-5p ; hsa-mir-4272 ; hsa-mir-6074 ; hsa-mir-7109-5p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-4326 ; hsa-mir-6885-5p ; hsa-mir-328-5p ; hsa-mir-6887-5p ; hsa-mir-6795-5p ; hsa-mir-637 ; hsa-mir-4729 ; hsa-mir-136-5p ; hsa-mir-548e-5p ; hsa-mir-1253 ; hsa-mir-3928-5p ; hsa-mir-449b-3p ; hsa-mir-6770-5p ; hsa-mir-6806-3p ; hsa-mir-6854-5p ; hsa-mir-1910-3p ; hsa-mir-3148 ; hsa-mir-3714 ; hsa-mir-4484 ; hsa-mir-548an ; hsa-mir-6511a-5p ; hsa-mir-651-3p ; hsa-mir-6768-3p

Nearest miRNA

hsa-mir-1286/Upstream/686529; hsa-let-7a-3/Downstream/263515;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/471379, chr22-CpG: 131/Downstream/4839

Upstream sequence

TCTACAAAGCAACTTCAGGCTATCTGGAACCCCTTCCCTGAAACCTGAAAGAAAGTCATCTTACTACTAGAATCAGCTGCTAATAGGAATAACTGCTGAA

Downstream sequence

CTTGGCTAAACTGGATTTATGACTCTATGGTGAGAAGCGGTTACTTGGCCATATAATAATTATACCATATCAACATTTCACTGACACAAAGAATTCTGCT

Target sequence

CCCA