Basic Information
VIS ID
TVIS10019080
Fusion event
HBV-THUMPD3-AS1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr3
Cytoband
p25.3
Reference genome
GRCh37/hg19
Start
9438781/9397097 (Hg38)
End
9438870/9397186 (Hg38)
Location type
Intron2
Target gene
THUMPD3-AS1
Nearest miRNA
hsa-mir-4790/Upstream/4146842; hsa-let-7g/Downstream/883165;
Nearest TSS
ENST00000440867/Upstream/65; ENST00000468208/Downstream/242;
Nearest CpG islands
chr3-CpG: 170/Target, None/Upstream, None/Downstream
Upstream sequence
GGTTAGAATGTCCTGTATCGGATGCCCCCCTTGCTGTTCATGTCACCAGAGGCCCTTGGAAGGTATCTACGGTGGAGTGTCCTTATTCTCAAAGCCACTG
Downstream sequence
TGGCTCCGTCCGGTTTCGAGCATTTTCCGCTCCCTTCTCCCTCCCCCTCCGGTTGCCGCAGGGCGGGCCTCCCTCCCGCCTGCATCCAGCCACCCCTTTC
Target sequence
CCATTTGTGTTTTCACACACGGCGGGAGGAGAAACGGCCAATCGGCGACAAGAGGCTAGCCGGAAGCGCTCCTCCCTCTGCGAGAGCAA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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