Basic Information
VIS ID
TVIS10019082
Fusion event
HBV-LOC105377110 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr3
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
59192369/59206643 (Hg38)
End
59192458/59206732 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA3B
Target gene
LOC105377110
Nearest miRNA
hsa-let-7g/Upstream/3354049; hsa-mir-12124/Downstream/1411073;
Nearest TSS
ENST00000440867/Upstream/141493; ENST00000475527/Downstream/181972;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/156425, chr3-CpG: 48/Downstream/2044200
Nearby gene
C3orf67-AS1
Upstream sequence
aatcattactgagcatgtagtatgtgccagatgTACATTCCTTTGGTCCTCACCTATGAGGAAGGCCTACTAATCTTCTGCTGAGAAAGATGAGGCTCCG
Downstream sequence
TTTAGCCTcttccttccttccttccttccttccttcccctcctgtccttcctttccttcTGTttcctttctctctctttctcttttctttttctctttct
Target sequence
tgctaagtagctcagaaccaaatctTCAGCACCTTTTACAAAAAGAAATGTGTTCCAGGAACCTTCTTATTTCCTTCTTGTTGTTTTTA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate