Basic Information
VIS ID
TVIS10019083
Fusion event
HBV-chr3 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr3
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
89851026/89801876 (Hg38)
End
89851156/89802006 (Hg38)
Nearest miRNA
hsa-let-7g/Upstream/2575599; hsa-mir-12124/Downstream/6557958;
Nearest TSS
ENST00000440867/Upstream/694200; ENST00000478400/Downstream/4109151;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/686919, chr3-CpG: 39/Downstream/4171704
Nearby gene
EPHA3
Nearest cancer related gene
EPHA3(TSG, No orient)
Upstream sequence
TCTTGAATAACTGCTGCAGCCGTAGTTAGCCCCCTATGAGCCAAGCCTATTGGCTTTGTTACTCCCAAGGTATAACTTATTTCATATATATAAGCAACTT
Downstream sequence
TGTAATTACATCACTAACACCTGAAGAAATGAAAGTTGATTAATGAGAAACAGATGCTAATTTTGAAGCCTGCAAATTCAAATATATTTAATAATGTGAA
Target sequence
TGCTGATTCAATAAGAAGTTTTATAGAAATTCCACATATCAGAGAAAATGCAGTTAAATCTAAATAGTAAAATTGATAATAACGATGTCACACTAATAAGAATACATGAAGCCAGGCTTGTACACCTGAC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate