Fusion event
HBV-ANXA3 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
79492239/78571085 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12113/Upstream/1995370; hsa-mir-1243/Downstream/4182252;
Upstream sequence
TCCTTCTTGCCCTGGTTTGTGGATGTCCTTGGTGGTTGCAATCAAGCAAGCTCTTATGAGGAATAATATCTGGAGAAAAGAAGAGAAGCATTTGAGAGTT
Downstream sequence
actgcagccttgaccttctgcgctcaagtggtcctcccacctcagcctcccaagtagctgggaccacacctgcacaccaccacacctggtaattttttaa
Target sequence
ATtttctttctttctttctttctttttttTTGtgagacacggtctcactctgtcacctagactacagtgcagtgacacaatcacagctc
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.