Basic Information
VIS ID
TVIS10019093
Fusion event
HBV-LOC105379107 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr5
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
103257639/103921938 (Hg38)
End
103257735/103922034 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA5F
Target gene
LOC105379107
Nearest miRNA
hsa-mir-10397/Upstream/3105373; hsa-mir-103a-1/Downstream/6591795;
Nearest TSS
ENST00000502646/Upstream/359145; ENST00000514769/Downstream/157877;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/662089, chr5-CpG: 253/Downstream/3747395
Nearby gene
NUDT12
Upstream sequence
ACAGCAGAGCGTACCATGCTGCAAGGAGTAATAAACAAGGAATTAGAAAACTCGCTGCTGGAGAACAGTCAAATTAAACACCTTTTTGAAAGGATGAGCA
Downstream sequence
caggtgcttgccaccacgcctggctaatttttgtatttttagtagagacggggtttcaccatgttggccaggctggtctgaaactcctgacctcagatga
Target sequence
ggctggagtgcaatgatgcaatctcggctcactgcaatcttcaactcccgggttcaagcgattctcccacctcagcctcctgggtagctgcaatta
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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