Basic Information
VIS ID
TVIS10019095
Fusion event
HBV-chr6 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr6
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
37062916/37095140 (Hg38)
End
37063453/37095677 (Hg38)
Fragile sites / regions
FRA6H
Nearest miRNA
hsa-mir-1236/Upstream/472628; hsa-mir-10398/Downstream/459688;
Nearest TSS
ENST00000381078/Upstream/73598; ENST00000468243/Downstream/74526;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/50032, chr6-CpG: 203/Downstream/73617
Nearby gene
PIM1
Nearest cancer related gene
PIM1(OG, No orient)
Upstream sequence
CAAAAGGAGCCAGAGCCCAGGGAGGAAACCAGATGGAAAGGGCTCTGCTCAGACCAATTCAATGCGGGAAGACAAGGGCACATGTGGGATAAAGGACATC
Downstream sequence
AGCTGACAATATGTGGCCAAGTGCTCCAAGAGCACTTGGAATATTGTGGCTCCAAGAGCTACAATAgtggctcacacctctaatcccagcactttgggag
Target sequence
ttgagcccaggaggtcgaggctgcagtgagccatgattgtgccactgcactcaccctgggcgacagattgagatcttgttgcaaaaaaagacaaaaacaaCAGATGCCTACAgagtgctcgattcgtgcccggctctgttacatagactaaaccctttcagttttcacaacttcatgaattaactactactatcatcagccatgtgtgatagatgagaatattagggcctattagtgctaaccttgcccaaggtc
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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