Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019097
Fusion event
HBV-PDE7B integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Host Sequence
Chromosome
chr6
Cytoband
q23.3
Reference genome
End
136509316/136188178 (Hg38)
Location type
Intron12
Target gene
miRNAs that regulate target gene
hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-7106-5p ; hsa-mir-149-3p ; hsa-mir-4736 ; hsa-mir-766-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-4662b ; hsa-mir-4647 ; hsa-mir-4426 ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-607 ; hsa-mir-6715b-3p ; hsa-mir-4717-3p ; hsa-mir-6715a-3p
Nearest miRNA
hsa-mir-10398/Upstream/948910; hsa-mir-1202/Downstream/2247035;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/690144, chr6-CpG: 51/Downstream/61804
Upstream sequence
ctaaaatgaccgcaaaaagacacttgcttatagtacgagagctaaaacaagaaagcagagtgttgctttatttgacctcagctaggaatgtgcatgttgt
Downstream sequence
CAGGAAATAAGGACAAAATAAATCTAGCTATAAAGATTTCAATGGAATATACAACTATTAAAATAGGTATGTTCGATTATTGAGCATTTTTTTTTTTCAA
Target sequence
TAAAATCATCCT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.