Basic Information
VIS ID
TVIS10019100
Fusion event
HBV-INHBA-AS1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr7
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
41764772/41725174 (Hg38)
End
41764861/41725263 (Hg38)
Location type
Intron2
Target gene
INHBA-AS1
Nearest miRNA
hsa-mir-1183/Upstream/4805742; hsa-mir-10399/Downstream/1425632;
Nearest TSS
ENST00000635602/Upstream/19340; ENST00000432845/Downstream/252659;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/19310, chr7-CpG: 105/Downstream/240206
Upstream sequence
ttatcctgctattctttttatgagtctggaaatttcacacatgctaggcagagagtacacctacatgaccagcctagataaaaactgtgtttcttgggca
Downstream sequence
CCTCAGCCTTTGGAAAGCTACCTTGTACTCTATCCACACTCAATAAACGCTGCTTAATAATGACAATGAGAATAAGTGTTCCATCTCACTTTTCTCCGGA
Target sequence
CAGGGTCCTCGTGAGTCATGAGTTCCGCCATGGCCCAGAGCTGCCAAAATGCCGTTCTTCCCCACACTTTTCCACAGGAACTGGGGGTG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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