TPK1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019102
Fusion event
HBV-TPK1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr7
Cytoband
q35
Reference genome
GRCh37/hg19
Start
144152953/144455860 (Hg38)
End
144152953/144455860 (Hg38)
Location type
Intron1
Target gene
TPK1
miRNAs that regulate target gene
hsa-mir-3064-3p ; hsa-mir-4704-3p ; hsa-mir-4717-3p ; hsa-mir-371a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p
Nearest miRNA
hsa-mir-10399/Upstream/1073060; hsa-mir-153-2/Downstream/2922157;
Nearest TSS
ENST00000635602/Upstream/45633; ENST00000637105/Downstream/190254;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/51813, chr7-CpG: 66/Downstream/379809
Upstream sequence
AACATCTTTTTTGATCTTCAAAACAGATAAGGGAAAGAGAGGCCTGATTAGCACCCCAAGTCCAAGGAAACAGAGAAGAGGAGCCTGGACAGTTACTCAC
Downstream sequence
ATATTTTTGGACAAAACCTTAGAAAAATAAAAAAATTTTAAGGAAAATATTTGGAATTATGATGAACTTCCTCTACCCCAAATATCTGAAGGCCAATCAT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate