MED30 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019105
Fusion event
HBV-MED30 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr8
Cytoband
q24.11
Reference genome
GRCh37/hg19
Start
118535416/117523177 (Hg38)
End
118535434/117523195 (Hg38)
Location type
Intron1
Target gene
MED30
miRNAs that regulate target gene
hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-4668-5p ; hsa-mir-513a-5p ; hsa-mir-3148 ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-6875-5p ; hsa-mir-5584-5p ; hsa-mir-3126-5p
Nearest miRNA
hsa-mir-12123/Upstream/648377; hsa-mir-10400/Downstream/1801976;
Nearest TSS
ENST00000518652/Upstream/2344; ENST00000519391/Downstream/7169;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/2105, chr8-CpG: 76/Downstream/588540
Upstream sequence
AACCCTAATTTTATTTTCTTTGGGAACAGGGTGGGGGTTTGGAGGGACTTTGAACTATAGGTATTTAAATTATTTTGAGAGCTTTTTTTTTTTTAAAGAA
Downstream sequence
TTTTTTTTTTTTAAGTTTTTTTTTTTTGTCTGTAAGTTTATTCAATGCAAAATAATCCTCTCCAATTTTACTGAGGTGGCTGACCATGTCCACGACCAAA
Target sequence
CCTGCATTCAAAGCCAAC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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