Basic Information
VIS ID
TVIS10019106
Fusion event
HBV-SAMD12-AS1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr8
Cytoband
q24.12
Reference genome
GRCh37/hg19
Start
119647429/118635190 (Hg38)
End
119647518/118635279 (Hg38)
Location type
Intron2
Fragile sites / regions
FRA8C ; FRA8E
Target gene
SAMD12-AS1
Nearest miRNA
hsa-mir-12123/Upstream/1760390; hsa-mir-10400/Downstream/689892;
Nearest TSS
ENST00000518652/Upstream/13195; ENST00000521788/Downstream/293794;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/13116, chr8-CpG: 24/Downstream/316428
Upstream sequence
TATAATTTAAAGGTGATAAAATACCACTTTGAGGTTATTGATAGAGTTCACACAGTGGCGTAGATGAGTAGTTCAGGCAAAGATCATCAACAAGGTGGTG
Downstream sequence
ATTTGAAGGACTATTCAGACAAGTAAGCAGTAGGCAGTATGCTGGGCACTAGAAATGAAAACATGAATACTACAAGTTTCCCCCGCTGAGAGCTGACCTT
Target sequence
TTCAATGCTTTTGGCATGTATCACTTTGGGCCTGATGGTAAAAGAGTCATATGCCTCATAAAGATTGCTTCCTTAGTCATGTAAAGAAC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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