Basic Information
VIS ID
TVIS10019108
Fusion event
HBV-CNTNAP3B integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr9
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
40330145/41901293 (Hg38)
End
40330145/41901293 (Hg38)
Location type
Intronic
Target gene
CNTNAP3B
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-101-2/Upstream/667458; hsa-let-7a-1/Downstream/28908682;
Nearest TSS
ENST00000422679/Upstream/1349; ENST00000496386/Downstream/4986;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/2205, chr9-CpG: 42/Downstream/51827
Nearby gene
LOC105379450
Upstream sequence
gtttcattgatactcccccatcccctcctcctctcctagGCAGCCTATTATTTCATCACAGttttcatttttgtgtttttgtttgagacagagcctcact
Downstream sequence
AGAGCTCAGTTTGAAAGCTTGCCTGAATGCCTGTCCGTGGGAAGAGCAGTCACCAGTCACTCCACCGCCCTCCAGCTTTGGATCAGGCCATTTTAACCTT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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