Fusion event
HBV-FAM171A1 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
15362714/15320715 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1265/Upstream/883965; hsa-mir-107/Downstream/2524392;
Upstream sequence
AGCAAGGTTAATATGACAAGTAGTTCTCTGGTGCCCAACATCGACAAAGTCCAGAAAGAAACTAAGCATCAGAGATCTAGCATGGATGGGAGGGACCTGA
Downstream sequence
aagcattttcttcctgtttgttggccatgtgtatgtcttcttttgagaagtgAGATTGGCCATTTTAGACCACACAGTAAGTTTGCACATAATAACTTTC
Target sequence
atgttattttttgactttttaataatagccattctgactggtatgagatggtatctcattgtggttttgatctgcatttctctaatgat
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.