Basic Information
VIS ID
TVIS10019116
Fusion event
HBV-chr12 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr12
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
51144836/50751053 (Hg38)
End
51144925/50751142 (Hg38)
Fragile sites / regions
FRA12A
Nearest miRNA
hsa-mir-1244-3/Upstream/516841; hsa-let-7i/Downstream/2147747;
Nearest TSS
ENST00000382841/Upstream/65167; ENST00000549612/Downstream/12568;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/245672, chr12-CpG: 139/Downstream/12573
Nearby gene
ATF1
Nearest cancer related gene
ATF1(OG, No orient)
Upstream sequence
agtatgatgaaaccctgtctctactaaaaatacacaaattatccgggcgtggtggcacgcgcctgtagttccagctacttaggaggctgaggcagaagag
Downstream sequence
aatacaaaaattagctggatgtggtggtggcgcatacctgtaatcccagctactggggaggctgaggcaggacaatcgcttgaacctgggaggcagagat
Target sequence
caccttgggaggctgaggtgggtggatcacctgaggtcaggtgttcaagaccagcctgatcaatgtggtgaaaccccatctgtactaaa
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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