Fusion event
HBV-MIPEP integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
24423491/23849352 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-4499/Upstream/3415417; hsa-mir-1267/Downstream/313064;
Upstream sequence
gcaactgctgtgaaaaacaacatggagttttctcaaaatatttaaaatagaactactatatgaaacagcaatcttacttctgggcatatatccaaaacat
Downstream sequence
TGCCATCCCTGTCACCACCTCAGACTCTTCTACAGTTTTACAAGAATTTTATGACTATTTTTTGTAAAGAATTCCATGGATCTGGACCCAGAAGTAAGGG
Target sequence
ACCATGGGCAGCATATAGGACCTCACAGCACAGCAGAGCCACAACCAGCAGAGACAGAGCTTAGATGCATTTTGAGGATTTGGCTTCAG
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.