Basic Information
VIS ID
TVIS10019120
Fusion event
HBV-chr13 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr13
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
57972544/57398410 (Hg38)
End
57972544/57398410 (Hg38)
Fragile sites / regions
FRA13B
Nearest miRNA
hsa-mir-1297/Upstream/2223862; hsa-mir-1267/Downstream/3801388;
Nearest TSS
ENST00000623511/Upstream/231213; ENST00000615375/Downstream/233400;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/230961, chr13-CpG: 58/Downstream/231042
Nearby gene
PRR20E
Upstream sequence
gttTTTTAAAGAAAATGAAACAAATATGAAAATTATTAGAGTCTATGTAGTAAAGTGGTAGGTATGGAAGGAGAATAGGCAAGGACACAAACACAGTTTT
Downstream sequence
TCTCTGGAACCCCAATCTGATTAATCCTTACATATTCAGTCTCTCAAAACAATTCATCTTCTGCCTTAGTTAGAAATCAGAAGTTCCAACAGGAGGTCTG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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