VISDB Viral Integration Site DataBase

VIS ID

TVIS10019125

Fusion event

HBV-TTLL5 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr14

Cytoband

q24.3

Reference genome

Start

End

76268093/75801750 (Hg38)

Location type

Intron27

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-4668-5p ; hsa-mir-3148 ; hsa-mir-3121-3p ; hsa-mir-548c-3p ; hsa-mir-143-5p ; hsa-mir-3944-5p ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-7157-3p ; hsa-mir-5008-3p ; hsa-mir-6737-3p ; hsa-mir-6889-3p ; hsa-mir-545-5p ; hsa-mir-7845-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-4475

Nearest miRNA

hsa-mir-208a/Upstream/1320321; hsa-mir-1185-1/Downstream/1464468;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/138954, chr14-CpG: 76/Downstream/180530

Upstream sequence

GTAAGCCATCCAGGAtttctatttgttcaatttctttttcccttctttattgaattcttttgaattgattgaggtttctggaataatcattacatgtttt

Downstream sequence

AATGGTTTAGTATAGATTCTGGTATATTTGTTTACTAACAGTTTCCCTTTTTCTCTAGTTATATTTAAAAAGAAAGTTGCTTTAGTTTCTTACTCACTGA

Target sequence

ttgggagtgttaaagaaccttgccttgtcatattaccagaattgtttttccggttccttctcatctgggtagtctgtatcagagggtctgggttgaagggctgctgttcagattcttttgtcccactggttggttccttgatgtggtgttctcttcttcccctagtagggatggggcttcctgagagccaaactgcagtgattgttactgcccttctgggtctagccccccagcagagctgctgggctctgggct