Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019127
Fusion event
HBV-ITGA11 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Host Sequence
Chromosome
chr15
Cytoband
q23
Reference genome
Start
End
68603371/68311033 (Hg38)
Location type
Exon5
Target gene
miRNAs that regulate target gene
hsa-mir-29a-3p ; hsa-mir-574-5p ; hsa-mir-3162-5p ; hsa-mir-135b-3p ; hsa-mir-6867-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-1321 ; hsa-mir-6760-5p ; hsa-mir-6757-5p ; hsa-mir-2278 ; hsa-mir-449b-5p ; hsa-mir-449a ; hsa-mir-34c-5p ; hsa-mir-34a-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6499-3p ; hsa-mir-1827 ; hsa-mir-4302 ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-6732-5p ; hsa-mir-6752-5p ; hsa-mir-6842-5p ; hsa-mir-7110-5p
Nearest miRNA
hsa-mir-10393/Upstream/1813981; hsa-mir-11181/Downstream/490817;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/32295, chr15-CpG: 118/Downstream/119995
Upstream sequence
ggttaggggttagggttaggggttaggggttaggggttagggttggggttagggttagggttagggttagggttagggttagggttagggttagggtagg
Downstream sequence
GGCCGGTACTCAGTGCTATTGCCCCAGATGTTACAGGACGTGTTCGCCTACATAAAGGACATGGACACACACACACATACACAGCCTCACAACCAGCTCT
Target sequence
TCTTCCTCCACTGGGGTG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.