L3MBTL4 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019128
Fusion event
HBV-L3MBTL4 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr18
Cytoband
p11.31
Reference genome
GRCh37/hg19
Start
6107802/6107803 (Hg38)
End
6107891/6107892 (Hg38)
Location type
Intron6
Target gene
L3MBTL4
miRNAs that regulate target gene
hsa-let-7b-5p
Nearest miRNA
hsa-mir-3976/Upstream/266970; hsa-mir-1-2/Downstream/266469;
Nearest TSS
ENST00000575820/Upstream/82712; ENST00000578427/Downstream/148855;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/211553, chr18-CpG: 22/Downstream/176483
Nearest cancer related gene
L3MBTL4(TSG, No orient, 0)
Upstream sequence
agggtgagggtgagggtgagggtgagggtgagggtgagggttagggttagggtgagggtgagggtgagggtgagggtgagggtgagggtgagggttaggg
Downstream sequence
TTTACCGAACACCACTTGTTTACTTTGTACCTTGTTTACTTTGCCCAAGTGACAAGTGAGAAACAGGATTAACCACTTGAGCTCCCCCAAAAATCGCGTG
Target sequence
GATGCATTCTCAAAGTTTCAGCCTGCTCACAGATTGGCCACTGCACATTTCGTGTATCTATTTAATATTGCCTGGAAATCTCCAAAGGT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate