Basic Information
VIS ID
TVIS10019131
Fusion event
HBV-chr18 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr18
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
71108242/73441007 (Hg38)
End
71108331/73441096 (Hg38)
Nearest miRNA
hsa-mir-1-2/Upstream/587625;
Nearest TSS
ENST00000575820/Upstream/571967; ENST00000581467/Downstream/274394;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/571371, chr18-CpG: 97/Downstream/706224
Nearby gene
LINC02582
Upstream sequence
TACCTAAAACAATTCTATCAGTGGTACATATGTGTAATATAATGATATTTTTACTATATTTAAGGTATATAAGAGAGTCTCCCAGGTTAAAACAAGAAAA
Downstream sequence
GGATTCAGGCTGTGTGATGAGAGGAGATATTTTCTCCACGTTGTGTGGGAAAGGCAGGGACAGGCAGCACATCTCTTGAATAGGAAACAATTTATGATCT
Target sequence
CTTGGAAAAGAGTATGGATGCAGAAAATGGAGACAAATGTCCTGGTTGAAGAGGTTCCATGGCTGAGCAGGCTGAGCAGGCAGTGTTAC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate