VISDB Viral Integration Site DataBase

VIS ID

TVIS10019141

Fusion event

HBV-IL6R integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr1

Cytoband

q21.3

Reference genome

Start

End

154394712/154422236 (Hg38)

Location type

Intron1

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-23a-3p ; hsa-mir-124-3p ; hsa-mir-125b-5p ; hsa-mir-98-5p ; hsa-mir-451a ; hsa-mir-34c-5p ; hsa-mir-34b-3p ; hsa-mir-34a-5p ; hsa-mir-619-5p ; hsa-mir-3619-3p ; hsa-mir-6807-5p ; hsa-mir-5095 ; hsa-mir-7151-3p ; hsa-mir-4529-5p ; hsa-mir-1292-3p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-4793-5p ; hsa-mir-6504-3p ; hsa-mir-4438 ; hsa-mir-335-3p ; hsa-mir-5096 ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-7156-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-4284 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-1184 ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-6890-3p ; hsa-mir-509-5p ; hsa-mir-509-3-5p ; hsa-mir-4418 ; hsa-mir-7641 ; hsa-mir-2052 ; hsa-mir-4695-3p ; hsa-mir-4330 ; hsa-mir-5680 ; hsa-mir-5197-5p ; hsa-mir-1537-3p ; hsa-mir-548ay-3p ; hsa-mir-548at-3p ; hsa-mir-221-5p ; hsa-let-7c-3p ; hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-126-5p ; hsa-mir-1277-3p ; hsa-mir-202-3p ; hsa-mir-219a-1-3p ; hsa-mir-331-5p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-4678 ; hsa-mir-4738-3p ; hsa-mir-4795-3p ; hsa-mir-495-3p ; hsa-mir-510-3p ; hsa-mir-515-5p ; hsa-mir-519d-5p ; hsa-mir-519e-5p ; hsa-mir-548ae-3p ; hsa-mir-548ah-3p ; hsa-mir-548aj-3p ; hsa-mir-548am-3p ; hsa-mir-548aq-3p ; hsa-mir-548j-3p ; hsa-mir-548x-3p ; hsa-mir-5582-3p ; hsa-mir-5688 ; hsa-mir-5695 ; hsa-mir-570-3p ; hsa-mir-630 ; hsa-mir-6509-5p ; hsa-mir-653-5p

Nearest miRNA

hsa-mir-101-1/Upstream/228493; hsa-mir-1182/Downstream/553457;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/16267, chr1-CpG: 196/Downstream/79395

Upstream sequence

ACACCTCTACCCATTTTCTCTTCCCCGGTGTCAGCGCCGCTCCTGACATCCAACCTCCATGTTCCCCCTTTTATTCTCCACTACCTTTGACCCGCGCGCT

Downstream sequence

GTCCTCCCCAATTTCTTCTTCTTCTTCAGCTGTAATTTTCCCCTGCTGTGCCTGAAAAAAAAAAAAAatatatatatatatatatatatatataCAGCAT