VISDB Viral Integration Site DataBase

VIS ID

TVIS10019154

Fusion event

HBV-TLR3 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr4

Cytoband

q35.1

Reference genome

Start

End

187005533/186084379 (Hg38)

Location type

Intron4

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-758-3p ; hsa-mir-137 ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-3163 ; hsa-mir-365b-3p ; hsa-mir-365a-3p ; hsa-mir-3662 ; hsa-mir-548e-5p ; hsa-mir-21-5p

Nearest miRNA

hsa-mir-12113/Upstream/1145780;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/445013, chr4-CpG: 123/Downstream/20199

Upstream sequence

agtcatattaaaatatacaattaaattgctgttgactatagtctccctgttgtgctatcaaataccaggtcttattcattctttttaaAAAtttccaact

Downstream sequence

ctggctaatttttgtatttttattagagatggggtttcaccgtgttggccaggcttatcttgaactcctggcctcaggtgaGCTTCAATTAAACTTTTAA

Target sequence

Atttctttttttttttttgagatggagtcctgctctgttgcccaggctggagtgcagtggtgtgatctcagcttactgcagcctccacctcctgggttcaagtaattctcctgcctcagcctctcaagtagttgggattacaggcacgcgccaccaagc