VISDB Viral Integration Site DataBase

VIS ID

TVIS10019158

Fusion event

HBV-PIK3R1 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr5

Cytoband

q13.1

Reference genome

Start

End

67586605/68290777 (Hg38)

Location type

Intron1

Target gene

miRNAs that regulate target gene

hsa-mir-29a-3p ; hsa-mir-376a-3p ; hsa-mir-29b-3p ; hsa-mir-21-5p ; hsa-let-7a-5p ; hsa-mir-155-5p ; hsa-mir-503-5p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-646 ; hsa-mir-6838-5p ; hsa-mir-448 ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-190a-3p ; hsa-mir-4524a-5p ; hsa-mir-5011-5p ; hsa-mir-4524b-5p ; hsa-mir-221-3p ; hsa-mir-1277-5p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-4793-5p ; hsa-mir-3924 ; hsa-mir-4789-5p ; hsa-mir-466 ; hsa-mir-455-5p ; hsa-mir-5580-3p ; hsa-mir-4643 ; hsa-mir-4789-3p ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-6721-5p ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-542-3p ; hsa-mir-218-1-3p ; hsa-mir-143-3p ; hsa-mir-128-3p ; hsa-mir-487a-3p ; hsa-mir-486-5p ; hsa-mir-1202 ; hsa-mir-126-3p ; hsa-mir-23a-3p ; hsa-mir-23b-3p ; hsa-mir-302a-5p ; hsa-mir-3658 ; hsa-mir-3972 ; hsa-mir-4317 ; hsa-mir-4755-3p ; hsa-mir-5006-5p ; hsa-mir-5007-5p ; hsa-mir-7856-5p ; hsa-mir-924

Nearest miRNA

hsa-mir-10397/Upstream/8586774; hsa-mir-103a-1/Downstream/3878690;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/1854, chr5-CpG: 62/Downstream/803073

Nearest cancer related gene

PIK3R1(OG, No orient, 0)

Upstream sequence

tatcctggcttctgttgttattTAGGATATGGGGTCTCACCTAACATTGGACAAAtgcaacgtggatcagagattgtgctcaggagtcagggaaattgaa

Downstream sequence

AGACAGATATAAATTGTGGCACAGACTTGATGTTTTATATAGAAATGGACCCACCAGGTAATACTGCAGTATTATTGTAGAGAGTTAGTTAATTTCGTGG

Target sequence

TGTATATATTGCAGTTCTATTAAATGTAGCTTCTTAGTGAGGTTGGCATTATGTTAAGGCTGGTATGGAAGAGAACTGATGAAGCAGGAGTGGTCTGGTGACATTTTTCTGACTTGATTGGCTGGGGCGTGTGATGTAATAGGTTTCAGTGCAGCCCCTTATAGGTTTTAAAATGAATTCCAAGACACCATTACAAAGAAAGCCGGACTCTTTTCTTATAACTGAGCTCAGCCAAGGAAACTCTTGCACAAATGT