VISDB - VIS Detail

Expression analysis of TCGA samples

Basic Information

VIS ID

TVIS10019162

Fusion event

HBV-PPIP5K2 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Nontumor

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

22634754

Virus Sequence

Virus name

HBV

Reference genome

NC_003977

Host Sequence

Chromosome

chr5

Cytoband

q21.1

Reference genome

GRCh37/hg19

Start

102457460/103121756 (Hg38)

End

102457460/103121756 (Hg38)

Location type

Intron1

Fragile sites / regions

FRA5F

Target gene

PPIP5K2

miRNAs that regulate target gene

hsa-mir-578 ; hsa-mir-6807-5p ; hsa-mir-526b-5p ; hsa-mir-1233-3p ; hsa-mir-1225-3p ; hsa-mir-5189-3p ; hsa-mir-4714-3p ; hsa-mir-1277-5p ; hsa-mir-5011-5p ; hsa-mir-190a-3p ; hsa-mir-340-5p ; hsa-mir-503-3p ; hsa-mir-4252 ; hsa-mir-6861-5p ; hsa-mir-186-3p ; hsa-mir-885-5p ; hsa-mir-3159 ; hsa-mir-541-5p ; hsa-mir-551b-5p ; hsa-mir-670-3p ; hsa-mir-6833-5p ; hsa-mir-4752 ; hsa-mir-644a ; hsa-mir-3190-3p ; hsa-mir-8053 ; hsa-mir-6717-5p ; hsa-mir-6077 ; hsa-mir-7-5p ; hsa-mir-145-3p ; hsa-mir-4289 ; hsa-mir-4302 ; hsa-mir-4482-3p ; hsa-mir-7159-3p ; hsa-mir-374a-3p ; hsa-mir-4291 ; hsa-mir-3160-5p ; hsa-mir-26a-2-3p ; hsa-mir-26a-1-3p ; hsa-mir-6731-3p ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-506-5p ; hsa-mir-892c-5p ; hsa-mir-136-3p ; hsa-mir-4762-3p ; hsa-mir-545-3p ; hsa-mir-3613-3p ; hsa-mir-548p ; hsa-mir-548e-5p ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p

Nearest miRNA

hsa-mir-10397/Upstream/2305191; hsa-mir-103a-1/Downstream/7392073;

Nearest TSS

ENST00000502646/Upstream/1148; ENST00000507310/Downstream/7550;

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/1470, chr5-CpG: 107/Downstream/136978

Upstream sequence

gaagcagtgggtaaagacattgactattacagcactcactgtttatccaaacagtatcccaggggagaatacatttcagggttctgtacgaggaaaactt

Downstream sequence

GTTGCTGTTTTAAATGTTAAATTCATATGACTTTCAGAGTAGTTGTTGTGAGGGTATTAAACTGAACAATTGGTAGAACATCTGTTGATTACCCAAATAA

Reference

Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.