Basic Information
VIS ID
TVIS10019166
Fusion event
HBV-LINC00271 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr6
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
135928529/135607391 (Hg38)
End
135929071/135607933 (Hg38)
Location type
Intron1
Target gene
LINC00271
Nearest miRNA
hsa-mir-10398/Upstream/368135; hsa-mir-1202/Downstream/2827280;
Nearest TSS
ENST00000381078/Upstream/109422; ENST00000579944/Downstream/22335;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/109369, chr6-CpG: 51/Downstream/642049
Upstream sequence
tgttccctgcgttgggagaacactgtttgcccaagcttacatcaaacacttagaaaactttagcaaaaattaaccacaaagcaggcaagtcagcaatttc
Downstream sequence
ATATTTGTTTTCCTCATTCTTTTTGTGAGTTTCTGCCCataaaatattttataataaaaatGCAAAAAAGATGAAGGTATCTTTTTTTACAAAACAGCAT
Target sequence
GAGTCCTGGCTCAAATTTTGTTTCATATCTCGTCATATCAAAATAAATAAGAATAAAAAATTACAATAATTGTGTTATTTTTCTATGTGAATATATATACACACAGCAGATtttatttaaccatttcctctgttattaaggaacttaaaacatttaagatatttccgaatcttcgccattgtttaaaataacactgaaatgagcatctgggtgcatatgtaattgcattcatctctaataatttccattggaaag
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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