Basic Information
VIS ID
TVIS10019174
Fusion event
HBV-VIRMA integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr8
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
95563641/94551413 (Hg38)
End
95563642/94551414 (Hg38)
Location type
Intron23
Fragile sites / regions
FRA8B
Target gene
VIRMA
miRNAs that regulate target gene
hsa-mir-877-3p ; hsa-mir-615-3p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-12123/Upstream/635294; hsa-mir-10400/Downstream/521497;
Nearest TSS
ENST00000518652/Upstream/7512; ENST00000523011/Downstream/2109;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/76280, chr8-CpG: 34/Downstream/2015
Upstream sequence
AACACTAGCAGTGCAGGGTTGAATCTTATACTTCCCTTTCTGGTTACACCCAGGCTCGTGCGGTCAGGTCTTCAGGCTCAGGGGCCAACTTTACCCTCAG
Downstream sequence
TCACAATTTTGTGAATCTAATCTCCAATACTGAGTTATAACTTCTTGAAAACAAACATTTCAATATTTCGTATCACCCACAaacccctacttcctccttc
Target sequence
A
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate