Basic Information
VIS ID
TVIS10019178
Fusion event
HBV-SLC24A2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr9
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
19806339/19806341 (Hg38)
End
19806339/19806341 (Hg38)
Location type
Intronic
Target gene
SLC24A2
miRNAs that regulate target gene
hsa-mir-1277-5p ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-6083 ; hsa-mir-4789-5p ; hsa-mir-4774-5p ; hsa-mir-4490 ; hsa-mir-340-5p ; hsa-mir-142-5p ; hsa-mir-5590-3p ; hsa-mir-4775 ; hsa-mir-29a-5p ; hsa-mir-590-3p ; hsa-mir-410-3p ; hsa-mir-4672 ; hsa-mir-6768-5p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-4474-5p ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-3922-5p ; hsa-mir-3142 ; hsa-mir-1245b-5p
Nearest miRNA
hsa-mir-101-2/Upstream/1232962; hsa-let-7a-1/Downstream/604807;
Nearest TSS
ENST00000422679/Upstream/19413; ENST00000568063/Downstream/119753;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/17051, chr9-CpG: 40/Downstream/128012
Nearby gene
SLC24A2
Upstream sequence
gcctagtttgttgagtgcgtgtgtgtgttttgtttgtttgtttgtttgtaatcatgaaaaggcataggattttgtaaatgctttttctgcatctattgtg
Downstream sequence
AGAGATAGGTGGTGAGGTCACAGTTGGGCCCTCTAGTAAGTCATGGATTCAACTGACTTAGGATATATAGTCTGTTTGGCTATTTGTATAGGATCTCATG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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