Basic Information
VIS ID
TVIS10019180
Fusion event
HBV-PLPPR1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr9
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
103835702/101073420 (Hg38)
End
103835702/101073420 (Hg38)
Location type
Intron1
Target gene
PLPPR1
Nearest miRNA
hsa-let-7a-1/Upstream/2844203; hsa-mir-12126/Downstream/5527508;
Nearest TSS
ENST00000422679/Upstream/44711; ENST00000494890/Downstream/58102;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/43938, chr9-CpG: 49/Downstream/325151
Upstream sequence
CTGTGGTACACCTTGGATGTTGGACAGGAGGGTGTGGCACGTGGTCTGGAGCTGCTGAGTCAGGTTGCGGGCAATTGCAAGAGTACGTGACTCAATGTGC
Downstream sequence
AGAAGAGGTCATGTGTGCAAATACCTTCTATTTGGAGGAGAGACTGCCTGACTTCATTTAAAGGTTACCTGTTTAACAATACTGTaattttcaacccaga
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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