Basic Information
VIS ID
TVIS10019182
Fusion event
HBV-chr10 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr10
Cytoband
p14
Reference genome
GRCh37/hg19
Start
6710330/6668368 (Hg38)
End
6710783/6668821 (Hg38)
Nearest miRNA
hsa-mir-3155a/Upstream/516091; hsa-mir-107/Downstream/5461939;
Nearest TSS
ENST00000439456/Upstream/49652; ENST00000417112/Downstream/68561;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/87688, chr10-CpG: 30/Downstream/503059
Nearby gene
MIR4454
Upstream sequence
TCTGTTCATTTTTCTTCACCACTTCTATCTTATTCCAAGTAATTTTTACCAGACTTGAAGCCCCTACTATAATCCCATAGGCACAGGATCTGTGTCTATG
Downstream sequence
TTAAATAAAAATTCTAGATCGTCCCAAAGTAAATCTGATCCACATAAGAAGTGAATTTGTAAAGCAGTTAAAATTGAGGAGTCTTCATTTGTTTTAGAAA
Target sequence
TCTTCCTTCTGGCATACTTCCCAGCACTTGCTTCTTCAGGGAGCAAGGCATGGCTATGAGGAACATGCGGCTTATAGTTATTTTCTGTGTTATGATATAGTTTGCTTCAGCATCCTTAAGTAACAAAGCCAGCTCTGCACATTTCAGATATAGTAATCTTCAGAAAGGTGCTGGTATTGGCTTGGGTGACACATTATTCACAATAAGCCAGAGAAAAGAAAAAATTGGACATGTAAAGGTGGGCATCTGGACTTT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate