Fusion event
HBV-chr16 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
33173073/33271832 (Hg38)
Nearest miRNA
hsa-mir-1225/Upstream/2376863; hsa-mir-11401/Downstream/891746;
Upstream sequence
TTTGTGAATGGAAATGTAGCAGGGCTTTTGCCTTTTTTCCTTGTTCATGAAAAACAAGTCGCGCTTGGGGAGCAAGTATTCCCGTTCAACTGCTGTCACT
Downstream sequence
GCTTTGTACAGCAACCAACACGAAAATGTTAACATACCACTGCAATAAATAGAATAAAAACATGTTCAGAAAGACTTAGAAACTCATTAAAGAATGGATA
Target sequence
ATGCAAAATACACTGTTTCTAAATTAAATTTTTTTGTAACAAAGAGTTTTTGAGTTCCCCTCATGAAATTTTAATAAATCATTAATTTCTTCTTTTTCTCTTTAATGCACAAGCAATGGATAAAACATTTCAAAGATCCCTACAGATGTTTCTTCACTTGAAATATTGTTCACATTACAATGAGAAGGATGGAATAAAACATAAAAAAGATAGGCAgttttgttttgttttgttttgttttgtttttaagatgga
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.