VISDB Viral Integration Site DataBase

VIS ID

TVIS10019205

Fusion event

HBV-CLTC integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr17

Cytoband

q23.1

Reference genome

Start

End

57738964/59661603 (Hg38)

Location type

Intron7

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-99a-3p ; hsa-mir-615-3p ; hsa-mir-503-5p ; hsa-mir-484 ; hsa-mir-106b-5p ; hsa-mir-92a-3p ; hsa-mir-16-5p ; hsa-let-7e-5p ; hsa-mir-4326 ; hsa-mir-544a ; hsa-mir-543 ; hsa-mir-377-3p ; hsa-mir-381-3p ; hsa-mir-485-3p ; hsa-mir-539-3p ; hsa-mir-487a-3p ; hsa-mir-376a-5p ; hsa-mir-382-5p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-1236-3p ; hsa-mir-6758-3p ; hsa-mir-877-3p ; hsa-mir-6891-3p ; hsa-mir-6072 ; hsa-mir-199a-5p ; hsa-mir-195-3p ; hsa-mir-574-3p

Nearest miRNA

hsa-mir-10226/Upstream/295284; hsa-mir-1250/Downstream/179663;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/41519, chr17-CpG: 28/Downstream/45790

Upstream sequence

GAATTATGATAAAAGAGAAGCCTTTTGTAAATGTGACTTGAAAAGTGGCGTATTTTGTGTCCTCTCTTTGTGTTTTATGCAGAATCCCTACTGCAGGACA

Downstream sequence

GCGAAAACAGCTTTTGGAGAAATGGTTAAAAGAAGATAAGGTACGTTAAATTATGTTGACATAATCTTGCTTTGGTTGCATTAAATATGATATTGGCAAG

Target sequence

AAAGGGAATTCTTCGTACTCCAGACACTATCCGTCGGTTCCAGAGTGTCCCAGCCCAGCCAGGTCAAACTTCTCCTCTACTTCAGTACTTTGGTATCCTTTTGGACCAGGGACAGCTCAACAAATACGAATCCTTAGAGCTTTGTAGGCCTGTACTTCAGCAAGG