Basic Information
VIS ID
TVIS10019210
Fusion event
HBV-chr19 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr19
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
33176086/32685180 (Hg38)
End
33176093/32685187 (Hg38)
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/12285826; hsa-let-7e/Downstream/2437513;
Nearest TSS
ENST00000633603/Upstream/8583; ENST00000397061/Downstream/6563;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/7987, chr19-CpG: 99/Downstream/6516
Nearby gene
NUDT19
Upstream sequence
aaaattaaaagtacaaaaaATCAgcctagcatagtggcacgcgcctgtaatcccagcactttgagaggccaacgcaggagaactgcttgagcccaggggt
Downstream sequence
ctcctgatctcaagtgatctgcctgctttggccccccaaagtgctgggagtacagatgtgaaccaccgcacTGGCTCGAGAATTTTAAAACTTTAAGGCT
Target sequence
tctcaaa
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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