Basic Information
VIS ID
TVIS10019212
Fusion event
HBV-chr21 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr21
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
31345802/29973484 (Hg38)
End
31346175/29973857 (Hg38)
Nearest miRNA
hsa-let-7c/Upstream/3019441; hsa-mir-3197/Downstream/401437;
Nearest TSS
ENST00000624081/Upstream/33451; ENST00000565564/Downstream/115860;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/33696, chr21-CpG: 24/Downstream/1277971
Nearby gene
CLDN17
Upstream sequence
caaaatcaaattgctgaaaaccaaataaaaagaaaacctgaaactttcattctttattgttgggaatgcaaaatgattcagcaaattttaatgatagttt
Downstream sequence
tacatttttggggaagtcaaaagttatacacaaagttttgactgtgcagtggtcatacctctagcccccatgttgttcaagggtcaactgtatacattta
Target sequence
ggccgttttcaattaagttacacagaattgagcgttgagcactatgggtttgaatggcacaagttgactaacatgtgaaattttcttctgcctctgccccctacaacagccagaccatccctccccttcctccttctcaatagtctaccaaatatgaacacaatgagaatgaagacctttatgatggtcctcttccacttaatgatttgtaaatatattatctctttctttatgattttcttaacattttctttt
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate