Basic Information
VIS ID
TVIS10019217
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr2
Cytoband
p15
Reference genome
GRCh37/hg19
Start
62773974/62546839 (Hg38)
End
62774687/62547552 (Hg38)
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1301/Upstream/340922; hsa-mir-10b/Downstream/1793195;
Nearest TSS
ENST00000437798/Upstream/34945; ENST00000467436/Downstream/115076;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/40477, chr2-CpG: 61/Downstream/157908
Nearby gene
TMEM17
Upstream sequence
ATATGATGCAGAATCTCTCTCAAGACTGCAGGCCTAGGATACATTTTTCTCTTTTTAGCAGCACTTCCAAAATTTTCAGGGATATTTTTCTAAGATAAAA
Downstream sequence
CCATTTCACTGTAATTAGTGTTCTTCATTCTATTCATGATTAAATACTCCAGTGTGTGTTGATCAAACCCCTTCTATTCAGAAACCTCATGCTCTCAACC
Target sequence
TAATCTGTTTTAAAAGTGAATTTCTGTGTAAAATAAAGAGCTTATTAAATGTAGGGTAATGAAGAAGTCTAGGGGGACCCTGTTCCATAACATCTCCATCATTTAGGAACTATATACATTTGCATTTACCTTTATGGCTTTTCTTTTGAAATTTTTGTCCTAATTTAAGTGACATCATTAAAACAAAAAAATGATGTCTATATAATATTGCTTCCTTTACTTAGCTATTTCACTTTTGTGGTTGACTGTTAAATT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate