ANXA4 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019218
Fusion event
HBV-ANXA4 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr2
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
70043380/69816248 (Hg38)
End
70043380/69816248 (Hg38)
Location type
Intron9
Fragile sites / regions
FRA2S ; FRA2E
Target gene
ANXA4
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-8061 ; hsa-mir-4760-5p ; hsa-mir-7161-5p ; hsa-mir-548u ; hsa-mir-3134 ; hsa-mir-1246 ; hsa-mir-4320
Nearest miRNA
hsa-mir-1301/Upstream/712493; hsa-mir-10b/Downstream/436670;
Nearest TSS
ENST00000437798/Upstream/1461; ENST00000468386/Downstream/13394;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/73788, chr2-CpG: 105/Downstream/13219
Upstream sequence
GAATCAATGAAACAGTCAAAAATCTAAAtttttttttttttttttttttttttaagacagagtctcactctgtcacccaggctgaagtgcagtggtgcga
Downstream sequence
TATTGCCCATAAGTAGTTGATAACCTTCCTCCTTCAGTTGGTACAAAGAACTGATTGTACCCAAGTGTCTTAGATTCTCACCCTGGAAATGTATTAGTCC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate