Fusion event
HBV-FN1 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
216245704/215380981 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10b/Upstream/1622733; hsa-mir-1244-1/Downstream/2519532;
Upstream sequence
ATACTGACAATATCCACTCTTAGGCACAACTACTAGTGTTTCTCTGCAGATAGAGAGAAAACAAAACAAAACACACAAAATAAAACACATTTTGATTTTT
Downstream sequence
CCCTGTACCTGGAAACTTGCCCCTGTGGGCTTTCCCAAGCAATTTTGATGGAATCGACATCCACATCAGTGAATGCCAGTCCTTTAGGGCGATCAATGTC
Target sequence
TCTGAGGCCTTGCAGCTCTGCAGTGTCTTCTTCACCATCAGGTGCAGGGAATAGCTCATGGATTCCATCCTCAGGGCTCGAGTAGGTCA
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.