Fusion event
HBV-FN1 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
216281048/215416325 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10b/Upstream/1656797; hsa-mir-1244-1/Downstream/2484188;
Upstream sequence
atcttctttaaaaaattgGGTTTTTcttgtaagtgagagctacatattgggtatccacggacataaacatggcaacagtagactctgggcactactgggg
Downstream sequence
TTAAAGTTGTATGTATTTCACAGAACACACAGGATGTTTGTTTTAATCAATTGGCATAAGTCAATTCCATGCCTATCTTTGAATTACCCCTTCTGTTTAT
Target sequence
GCCTGAAAATGAAAATGTAGCATTTAATTATCTTGAATATTCACTCACTTCAACTTAAAACTGTGTACATGGACAGTCATCATTATAAACAGCTTTGCTTGTCGTTAAATGTGAGTATAATAAAATTATCTGGCATTAATCTTTTAAATATTTACGTTGAAAATCAATGCAGCAAATCCATTTTTAGCCGATAATTATTATTCTTCACATGAGAAATGCAAATCATAGTTGTTTATAGCaaataaaatatatttt
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.