VISDB Viral Integration Site DataBase

VIS ID

TVIS10019226

Fusion event

HBV-FNDC3B integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr3

Cytoband

q26.31

Reference genome

Start

End

172029353/172311563 (Hg38)

Location type

Intron11

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-143-3p ; hsa-mir-335-5p ; hsa-mir-155-5p ; hsa-mir-124-3p ; hsa-mir-1-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-98-5p ; hsa-mir-30a-5p ; hsa-mir-26b-5p ; hsa-mir-378a-3p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-mir-495-3p ; hsa-mir-5688 ; hsa-mir-32-5p ; hsa-mir-92b-3p ; hsa-mir-373-5p ; hsa-mir-616-5p ; hsa-mir-888-5p ; hsa-mir-4649-3p ; hsa-mir-371b-5p ; hsa-mir-181a-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-181d-5p ; hsa-mir-218-5p ; hsa-mir-6516-5p ; hsa-mir-6874-5p ; hsa-mir-455-3p ; hsa-mir-6880-5p ; hsa-mir-6799-5p ; hsa-mir-3622b-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6500-5p ; hsa-mir-4633-3p ; hsa-mir-4327 ; hsa-mir-6499-3p ; hsa-mir-4722-5p ; hsa-mir-6134 ; hsa-mir-1827 ; hsa-mir-1247-3p ; hsa-mir-4768-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-5197-5p ; hsa-mir-9-3p ; hsa-mir-6835-3p ; hsa-mir-4422 ; hsa-mir-6513-5p ; hsa-mir-3656 ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-6788-5p ; hsa-mir-1273h-5p ; hsa-mir-30c-2-3p ; hsa-mir-7977 ; hsa-mir-30c-1-3p ; hsa-mir-675-5p ; hsa-mir-4466 ; hsa-mir-6848-5p ; hsa-mir-6846-5p ; hsa-mir-4283 ; hsa-mir-4437 ; hsa-mir-4284 ; hsa-mir-744-5p ; hsa-mir-4749-5p ; hsa-mir-4706 ; hsa-mir-342-3p ; hsa-mir-383-3p ; hsa-mir-1228-3p ; hsa-mir-1273a ; hsa-mir-4696 ; hsa-mir-6501-3p ; hsa-mir-451b ; hsa-mir-3145-5p ; hsa-mir-4432

Nearest miRNA

hsa-let-7g/Upstream/1204715; hsa-mir-1224/Downstream/3057977;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/270540, chr3-CpG: 107/Downstream/136019

Nearest cancer related gene

FNDC3B(OG, No orient, 0)

Upstream sequence

ATGTCACCGGGCAGGCGGTGCCTCTAATACTGATAATGCTAGAGGTGATGTTTTTGGTAAACAGGCGGGGTAAGATTTGCCGAGTTCCTTTTACTTTTTT

Downstream sequence

CATTTCTAAAAAGCAACTGTAggtcgggcgcgatgactcacgcctgtaatcccagcactttgggaggccaaggcaggtggatcacgaggtcaggagatca

Target sequence

TGTGCCAACTGGTGGACCCAGTGCATTTCTGGCCTAGCTAACTCTACACACAGAATCTCAGGCAGGAAACACTTGACCTAGAAGCCTTT