Basic Information
VIS ID
TVIS10019227
Fusion event
HBV-UVSSA integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr4
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
1348290/1354502 (Hg38)
End
1348379/1354591 (Hg38)
Location type
Intron5
Target gene
UVSSA
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-15b-5p
Nearest miRNA
hsa-mir-571/Upstream/1004250; hsa-mir-12113/Downstream/631793;
Nearest TSS
ENST00000502981/Upstream/6796; ENST00000507422/Downstream/11486;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/6819, chr4-CpG: 16/Downstream/15767
Upstream sequence
aaaattgtaaatcgagcaattgtttaagttggaaaatgtcCACATAGCCTCTCCCGTTATCAACATCCCTACCACTGTTTTACTGGGTAACCTGTGTCCA
Downstream sequence
GTTTGGGATTCCCGGGGGCAGGCATGGGCGTCTGGCAGGTTCCCCTCAGGCTAGAGCAGCCTTCCTTGCATGGTCTGCCTCTCCGGGGCCTGTGGGAGAC
Target sequence
CAGTGGAGCTGCGTGTGAGGGGAGGCTTTGGTGTTAAGCCACAGTGTTCTTTTCTAAGATAATAAAACACTTCCTTCTCACAGCATCAG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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