Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019234
Fusion event
HBV-ZNF292 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Host Sequence
Chromosome
chr6
Cytoband
q14.3
Reference genome
Start
End
87947770/87238052 (Hg38)
Location type
Intron5
Target gene
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-21-5p ; hsa-mir-196a-3p ; hsa-mir-7153-5p ; hsa-mir-146b-5p ; hsa-mir-146a-5p ; hsa-mir-3925-5p ; hsa-mir-3120-3p ; hsa-mir-32-3p ; hsa-mir-1273g-3p ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-508-5p ; hsa-mir-200a-3p ; hsa-mir-141-3p ; hsa-mir-6873-3p ; hsa-mir-4795-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-3675-3p ; hsa-mir-7151-5p ; hsa-mir-5003-3p
Nearest miRNA
hsa-mir-10398/Upstream/8698743; hsa-mir-1202/Downstream/3074690;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/81993, chr6-CpG: 30/Downstream/84387
Nearest cancer related gene
ZNF292(TSG, No orient, 0)
Upstream sequence
gctgggcgcggtgcctcatgcctgtaatcccagcactttgggaggccaaggcaggcagattacttgaggggaggagtttgagaacagcctggccaacatg
Downstream sequence
CACCATGAAAATTGTTTCATTAGTATGCCTATGAGAAATGAAGTTTGCTGTGTTACTGAATGTAGCAGATGTTTCAGTTGGTATGTTGCATGTATATGAA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.