VISDB Viral Integration Site DataBase

VIS ID

TVIS10019235

Fusion event

HBV-SYTL3 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr6

Cytoband

q25.3

Reference genome

Start

End

159132369/158711337 (Hg38)

Location type

Intron8

Target gene

miRNAs that regulate target gene

hsa-mir-449c-3p ; hsa-mir-486-3p ; hsa-mir-6721-5p ; hsa-mir-5787 ; hsa-mir-4505 ; hsa-mir-4731-5p ; hsa-mir-4722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-219b-3p ; hsa-mir-4768-3p ; hsa-mir-302f ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-5690 ; hsa-mir-890

Nearest miRNA

hsa-mir-10398/Upstream/100698; hsa-mir-1913/Downstream/53324;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/65726, chr6-CpG: 147/Downstream/106909

Upstream sequence

gggggatgtgtgcagattttcagggttttctcttcattcagctctctcctcttcagtattctttcctgtaaactccagccatatttgtctccccaaactc

Downstream sequence

ttagggttctccagatagacacagccaataggatatgtatatagatacatgagaggagtcttactaggggaattggctcacgtgatcacggcagctgaga

Target sequence

tactttgaagcatggagtcagttttcaaaaaaaaaaaaatgcataacacaaattaaaactctaaaagtgtctgtaatttttacctccagcatgggacatgatgagaacgtgaactacacagcatagcaaactgtgctgtgtgtgaaggggcagaattcatacacaactaaactaaataatttggcagcggagatttcttgtattttttttgcctgtgtttttacttctaagatctttgaaacacttgctgcactt