VISDB Viral Integration Site DataBase

VIS ID

TVIS10019238

Fusion event

HBV-NCALD integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr8

Cytoband

q22.3

Reference genome

Start

End

103094575/102082347 (Hg38)

Location type

Intron5

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-2053 ; hsa-mir-6780a-3p ; hsa-mir-4775 ; hsa-mir-569 ; hsa-mir-4635 ; hsa-mir-32-3p ; hsa-mir-203a-3p

Nearest miRNA

hsa-mir-12123/Upstream/1378348; hsa-mir-10400/Downstream/43085;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/587170, chr8-CpG: 81/Downstream/41339

Upstream sequence

AAATTGTATTGAAACAAAAATAGAGAAAAATACTGAAATAGATACAATGTTTTTAAAACAAGCAAATTTTATTAAAGGAAAATTTTGCAGGTTTAAGGTT

Downstream sequence

ctcagcctcctgagtagctgggactacaggtgccagccaAAAGCTCTCTTTAAAGGTATGATTGACACCTGAGCTCTCTGTCCCTGCCAGAAATTGATAC

Target sequence

TTTCACTGTCTCAACAAAGCCCTTTTCATATAGAAAATTGATCCTTAATGTCGTTGGTAACACACTGATGGAAATAAAAGTATGCTGTGGCACAAACGGGCCCTGGGCTTCAAAACAGTTTAGCTCATTTACGCCTATTTCTGATTTAAGTCAAGGAGAATTCAAATAATGGTaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaCCCCAAAAAAAACTGGCTTTGCGCATGCGCACTTTACCTCTTCCGAACTCT