UNC13B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019240
Fusion event
HBV-UNC13B integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr9
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
35214350/35214353 (Hg38)
End
35214439/35214442 (Hg38)
Location type
Intron1
Target gene
UNC13B
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-221-3p ; hsa-mir-92a-3p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-101-2/Upstream/1746418; hsa-let-7a-1/Downstream/393652;
Nearest TSS
ENST00000422679/Upstream/52249; ENST00000485086/Downstream/13356;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/51941, chr9-CpG: 89/Downstream/275265
Upstream sequence
TGAGAGGCCCCACTGACCTCAGTCTGTTTCTCACTGGAGCGCAGGTTTGGGAGCAGCAGCAACACCACATCCTTCGGCACGCTCGCGAGTCAGAATGCCC
Downstream sequence
tcaacaacaacaacaagaacaaaacaaaagaaactaggtatatttgaaaaagaaccaaaaagaaaaactcaagggaaaagttaaacaagtgaagagtatt
Target sequence
gaggcagaggttgcagtgagtggagatcgcaccactgtattccagcctaggcaacagaacaagactctgtctcaaaaacaaacaaacaa
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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