Fusion event
HBV-KIRREL3 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
126830241/126960345 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7a-2/Upstream/3578365; hsa-mir-3167/Downstream/28113;
Upstream sequence
tgtgattcatcacacaaacataattaaaaacaaaaaccacattaccatctcaataaatgcaggacaaacatccactaaaattcagcatccttaatgacta
Downstream sequence
GGGTTTGTCATTTTCAGATATCCAGCCGAGGACACTGAACCAAACGTAGTTTTTCTAAAGAGGCCCTAGGTTATATTTAAAGTTCTCCCAGTGCTCACTC
Target sequence
ACTGCTATAGACCACGTGTCACCATTGCTCGTACTCACTGCACATGTTTGTATAAGCCTTTCTACGCTGGATTCTGTACTCCTTCTGGGTAGGAATCCTCACTGATCCACTGTTTATTGTTTTTTTAATCCCTCAGTTCTCAGCAATGTACTTAGCCAATATTAGATACTTAGCACATGACTGACATCtgaatgaatgattgaatgaatgaatgaCTTCCCTTGGAAGTCCATGGGGTATAGGGAAGGAGGCAGA
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.